ACETAMINOPHEN INJ
Clinical Criteria Summary
Exclusion Criteria
- Severe hepatic impairment or severe active liver disease
- Hypersensitivity to acetaminophen or any components of the injectable formulation
Inclusion Criteria
- Acute Postoperative Pain Management
- Requires management of acute postoperative pain AND either patient is medically unable to take analgesics orally (NPO) or is unlikely to have sufficient gastrointestinal absorption to achieve benefit from ingested acetaminophen
- Patients with one or more hours available before the induction of general anesthesia for intraabdominal or oropharyngeal surgery (and likely adequate gastrointestinal absorption) should be preferentially prescribed ingestible oral liquid acetaminophen
- Patients having non-abdominal or non-oropharyngeal surgery and likely adequate gastrointestinal absorption may be given acetaminophen oral formulations at any time before induction of general anesthesia
- Non-Surgical Setting (Acute Pain or Fever Management)
- Requires management of acute pain or management of fever AND patient is medically unable to take analgesics orally (NPO) or is unlikely to have sufficient gastrointestinal absorption to achieve benefit from ingested acetaminophen AND (for pain control only) IV/IM ketorolac is contraindicated
- Patients with difficulty swallowing but likely to have adequate gastrointestinal absorption may be given oral liquid acetaminophen or ibuprofen suspension unless contraindicated