EDARAVONE INJ,SOLN
Clinical Criteria Summary
Exclusion Criteria
- Notably decreased respiratory function and dyspnea (total score of 3 or less points on ALSFRS-R items for dyspnea, orthopnea, or respiratory insufficiency)
- Bilevel positive airway pressure (BiPAP) dependent (use 24 hours per day)
- Other medical illness that will limit evaluation of motor function and efficacy (e.g., Parkinson’s disease, schizophrenia, significant dementia, other major medical morbidity)
- Other possible causes for current symptoms as applicable not ruled out (e.g., cervical spondylosis or multifocal motor neuropathy)
Inclusion Criteria
- Care provided by a VA/VA Community Care neurologist or locally designated ALS expert
- Diagnosis of ALS made or confirmed by a VA/VA Community Care neurologist or locally designated ALS expert
- Documentation of an itemized ALSFRS-R score in the electronic medical record
- Preserved function in either upper limbs (e.g., self-feed, self-dressing, typing) or lower limbs (e.g., walking)
- Discussion with patient/caregiver/family regarding realistic treatment expectations and discontinuation of therapy documented in the patient’s medical record