ESTRADIOL CREAM,VAG
Clinical Criteria Summary
Systemic Hormonal Menopausal Therapy (Oral Estrogen Combinations)
- Dosing Criteria: 0.45 mg conjugated equine estrogens/20 mg bazedoxifene daily
- Clinical Use Criteria: Bazedoxifene is an alternative to progestin for patients with a uterus
- Systemic Estrogen Formulary Requirements:
- Prescribe the lowest effective dose of estrogen
- Product selection should consider patient symptoms, risk-benefit profile, and patient preference
- A progestin (or bazedoxifene alternative) must be prescribed for all patients with an intact uterus receiving systemic estrogen to reduce endometrial hyperplasia and cancer risk