OLEZARSEN INJ,SOLN
Clinical Criteria Summary
Exclusion Criteria
- Serious hypersensitivity reaction to olezarsen
- Severe hypertriglyceridemia due to multifactorial chylomicronemia syndrome (MCS) or other causes, including secondary causes
Inclusion Criteria
- Provider is a VA or VA Community Care Cardiologist, Endocrinologist, or designated lipid expert with experience in managing familial lipid disorders
- Genetically confirmed diagnosis of familial chylomicronemia syndrome (FCS)
- Commitment to adhering to a fat restricted diet of <20 grams/day
Additional Inclusion Criteria
- For patients who can become pregnant: Counseling provided on potential risks vs benefits of treatment and the use of effective contraception during therapy