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PLOZASIRAN INJ,SOLN

Clinical Criteria Summary

Inclusion Criteria

  • Provider is a VA or VA Community Care Cardiologist, Endocrinologist, or designated lipid expert with experience in managing familial lipid disorders.
  • Patient has a genetically confirmed diagnosis of familial chylomicronemia syndrome (FCS).
  • Patient commits to adhering to a fat restricted diet of <20 grams/day.

Exclusion/Not Candidate Criteria

  • Document explicitly lists "None" under formal exclusion criteria.
  • Patients with severe hypertriglyceridemia due to multifactorial chylomicronemia syndrome (MCS) or other causes, including secondary causes, are not candidates.
  • Patients with mixed hyperlipidemia are not candidates.

Additional Inclusion Criteria

  • For patients who can become pregnant: Counseling provided on potential risks vs benefits of treatment and the use of effective contraception during therapy.

Source Documents