← Back to Drug List

POMALIDOMIDE CAP,ORAL

Clinical Criteria Summary

Exclusion Criteria

  • Absolute neutrophil count (ANC) < 500/mm3
  • Hemoglobin < 8 g/dL; Must transfuse to hemoglobin above 8 gm/dL prior to therapy initiation
  • Platelet count < 50,000/mm3
  • Eastern Cooperative Oncology Group performance status > 2
  • Patient has not been screened for Hepatitis B Virus
  • Active or uncontrolled infection
  • Known pregnancy
  • Lactating

Inclusion Criteria

  • Relapsed or refractory multiple myeloma, following at least 2 lines of therapy that included lenalidomide and a proteasome inhibitor
  • Diagnosis of Kaposi sarcoma

Additional Inclusion Criteria

  • Care is provided by a VA or VA Community Care hematology/oncology provider
  • Goals of care and role of Palliative Care consult have been discussed and documented
  • Venous thromboembolism (VTE) risk scoring (i.e. SAVED, IMPEDE) performed for consideration of VTE prophylaxis

REMS & Pregnancy Safety Requirements

  • Patients who can become pregnant and patients with partners who can become pregnant must comply with pregnancy testing and contraception requirements for pomalidomide under the POMALYST REMS program

Source Documents